Magnetic Resonance Imaging (MRI)
Image Analysis
Dr Canuto joins St Catharine’s from Fitzwilliam College where she has been an Admissions Tutor (Sciences), College Lecturer, Director of Studies and Tutor. She is also Director of Pre-Clinical Medical and Veterinary Education at the University of Cambridge’s School of Biological Sciences. As an inorganic and physical chemist, she has a particular research interest in magnetic resonance spectroscopy, especially biomedical imaging.
Booth Tom C; Larkin Tim J; Yuan Yinyin; Kettunen Mikko I; Dawson Sarah; Scoffings Dan; Canuto Holly C; Vowler Sarah; Kirschenlohr Heide; Markowetz Florian; Jefferies Sarah; Brindle Kevin M. Analysis of Heterogeneity in T2-Weighted MR Images can Differentiate Pseudoprogression from Progression in Glioblastoma. PLoS One. 2017.
Larkin Tim J; Canuto Holly C; Kettunen Mikko I; Booth Tom C; Hu De-en E; Krishnan Anant S; Bohndiek Sarah E; Neves Andre A; McLachlan Charles; Hobson Michael P; Brindle Kevin M. Analysis of image heterogeneity using 2D Minkowski functionals detects tumor responses to treatment. Magn Reson Med. 2014, 71: 402-410.
Canuto Holly C; Fishbein, Kenneth W; Huang Alice, Doty, Stephen B, Herbert; Ron A; Peckham, John; Pleshko Nancy and Spencer, Richard G. Characterization of skin abnormalities in a model of Osteogenesis Imperfecta using High Resolution Magnetic Resonance Imaging and Fourier Transform Infrared imaging spectroscopy. NMR Biomed. 2012, Jan 25(1): 169-76.
Asemu, Girma; Fishbein, Kenneth W; Lao Z. Qi, Ravindram, Arippa; Herbert, Ron; Canuto, Holly C; Spencer, Richard G; Soldatov, Nikolai M; Cardiac phenotype induced by a dysfunctional α1C transgene. Channels 2011 March/April (5:2): 1-10.
Canuto, Holly C; Kettunen Mikko I; McLachlan Charles; Krishnan Anant S; Neves Andre’ A; Hu De-en; Hobson Michael P; Brindle Kevin M. Characterization of Image Heterogeneity Using Minkowski Functionals. Proc. Intl. Soc. Mag. Reson. Med. 16, 2009.
Canuto, Holly C; McLachlan Charles; Kettunen Mikko I; Velic Marko; Krishnan Anant S; Neves Andre’ A; de Backer Maaike; Hu De-en; Hobson Michael P; Brindle Kevin M. Characterization of image heterogeneity using 2D Minkowski Functionals increases the sensitivity of detection of a targeted MRI contrast agent. Magnetic Resonance in Medicine 2009 Feb 27;61(5):1218-1224.
Canuto, Holly C; McLachlan Charles; Kettunen Mikko I; Velic Marko; Krishnan Anant S; Neves Andre’ A; de Backer Maaike; Hu De-en; Hobson Michael P; Brindle Kevin M. Increasing the sensitivity of detection of targeted MRI contrast agents using Bayesian image analysis methods. Proc. Intl. Soc. Mag. Reson. Med. 16, 2008.
Aime, Silvio; Chierotti, Michele R; Gobetto, Roberto; Masic Admir; Napolitano, Fabio; Canuto, Holly C; Heyes Stephen J: “Intramolecular Host-Guest Dynamics of FeCp(CO)2X (X = I and CH3) and Mo2Cp2(CO)6 Included in β or γ - Cyclodextrin”. Eur. J. Inorg. Chem., 2008, (1):152-157
Fishbein, Kenneth W; Canuto, Holly C; Preeti Bajaj; Nancy P. Camacho; Spencer Richard G. S: “Optimal methods for the preservation of cartilage samples in MRI and correlative biochemical studies”. Magn Reson Med, 2007 Apr 24; 57(5):866-87.
Asemu, Girma; Fishbein, Kenneth W; Canuto, Holly C; Abernethy, Darrell R; Soldatov, Nikolai M; Spencer, Richard G; In Vivo MRI Studies of Cardiac Morphology and Function in Overexpressing the Exon 22 Isoform of the Human Cav1.2α 1C Channel. Proc. Intl. Soc. Mag. Reson. Med. 16, 2007.
Canuto, Holly C; Oliveira, Miguel L. R; Fishbein, Kenneth W; Spencer, Richard G. S: “Tendon and neurovascular bundle displacement in the palm with hand flexion and extension: an MRI and gross anatomy correlative study”. Journal of Magnetic Resonance Imaging, 2006, 23(5), 742-746.
Canuto, Holly C; Heyes, Stephen J; Aime, Silvio; Gobetto, Roberto; Masic, Admir. A 13C CP/MAS NMR Study of the Structure and Dynamics of [(h5-C5H5)2Fe2(CO)4] Included in γ-Cyclodextrin: Evidence for Terminal-Bridging Exchange in the Cis Isomer. Organometallics, 2006, 25, 2248-2252.
Canuto, Holly C; Oliveira, Miguel L. R; Fishbein, Kenneth W; George, Christopher, Spencer, Richard G. S. MRI Analysis of zone III palmar anatomy with hand flexion and extension. Proc. Intl. Soc. Mag. Reson. Med. 13, 2005.
Canuto Holly C; Fishbein Kenneth W; Spencer Richard. G. S; Camacho Nancy P. Characterization of Skin Abnormalities Associated with Osteogenesis Imperfecta via High Resolution Magnetic Resonance Imaging. Proc. Intl. Soc. Mag. Reson. Med. 13, 2005.
Canuto, Holly C; Heyes, Stephen J; Green, Malcolm L. H; Higgins, John W; Abstr. Pap. – Am Chem. Soc., 2001, 221st INOR-102.AN 2001:20122.
Canuto, Holly C; Heyes, Stephen J; Aime, Silvio; Gobetto, Roberto; Napolitano, Fabio. The role of molecular shape and axial symmetry in the solid state molecular dynamics of metal carbonyl compounds included in cyclodextrin cavities. J. Chem. Soc., Dalton Trans., 2000, 4075-4077.
Aime, Silvio; Canuto, Holly C; Gobetto, Roberto; Napolitano, Fabio. Fast carbonyl exchange in the solid state for β-cyclodextrin/(arene)Cr(CO)3 inclusion complexes. Chem. Commun. 1999, 281-282.